NanoViricides, Inc. (OTC BB: NNVC.OB) announced that a recent animal study of it's FluCide drug candidate, showed a quadrupling in efficacy over a previous study.
In the study, mice were aspirated with one million virus particles of the H1N1 flu virus. The mice were treated with both FluCide and Tamiflu 24 hours later. The results show that the mice treated with Tamiflu survived only 8.3 days, while the FluCide treated mice were able to hold on for 20.2 to 22.2 days.
The full announcement is here:
http://www.businesswire.com/news/home/20110321005653/en/NanoViricides-Reports-Treatment-FluCide-Drug-Candidate-Achieves
Showing posts with label virus. Show all posts
Showing posts with label virus. Show all posts
Tuesday, March 22, 2011
Thursday, February 10, 2011
Time: A new project to track animal diseases before they infect humans
A new report from Time Magazine cites examples of diseases that have jumped from animals to humans.
http://healthland.time.com/2011/02/08/a-new-project-to-track-animal-disease-before-they-infect-humans/
"The virus that would trigger the H1N1/A pandemic in the spring of 2009 emerged in Mexico, and appeared to jump not from birds but from pigs. (Hence the term "swine flu.") It was as if the world's epidemiologists has been preparing for an invasion from the east only to be hit in our soft underbelly. While the Mexican government should be applauded for reacting to the new virus relatively well — and more importantly, in an open fashion — the fact that it emerged in a medical blind spot almost certainly slowed the international reaction to the new pandemic. Luckily, H1N1/A ended up being fairly weak, but if the virus had been a killer on level with the 1918 pandemic, that lost time could have meant lost lives.
Read more: http://healthland.time.com/2011/02/08/a-new-project-to-track-animal-disease-before-they-infect-humans/#ixzz1DZfWwtbr"
The Global Viral Forecasting project http://www.gvfi.org/ is trying to predict and prevent future pandemics.
http://healthland.time.com/2011/02/08/a-new-project-to-track-animal-disease-before-they-infect-humans/
"The virus that would trigger the H1N1/A pandemic in the spring of 2009 emerged in Mexico, and appeared to jump not from birds but from pigs. (Hence the term "swine flu.") It was as if the world's epidemiologists has been preparing for an invasion from the east only to be hit in our soft underbelly. While the Mexican government should be applauded for reacting to the new virus relatively well — and more importantly, in an open fashion — the fact that it emerged in a medical blind spot almost certainly slowed the international reaction to the new pandemic. Luckily, H1N1/A ended up being fairly weak, but if the virus had been a killer on level with the 1918 pandemic, that lost time could have meant lost lives.
Read more: http://healthland.time.com/2011/02/08/a-new-project-to-track-animal-disease-before-they-infect-humans/#ixzz1DZfWwtbr"
The Global Viral Forecasting project http://www.gvfi.org/ is trying to predict and prevent future pandemics.
Monday, February 7, 2011
Universal Flu Vaccine - too good to be true?
Testing of universal flu vaccine has found early success. A small scale study at Oxford's Jenner Institute found promising results for tests of the feasibility of a possible universal vaccine that could one day replace the yearly flu shot.
According the to report on the medical site, WebMD, "such a vaccine could also help prevent pandemics such as the recent outbreaks of H1N1 swine flu.
Traditional flu vaccines target proteins that sit on the virus’s outside coat and harness the body’s existing antibodies to fight infection. However, these proteins tend to mutate, meaning that manufacturers have to develop new vaccines.
The new treatment targets proteins inside the flu virus that are common across all strains and use existing antiviral T cells to attack the virus."
http://www.webmd.boots.com/cold-and-flu/news/20110207/early-success-for-universal-flu-vaccine
Longer article about this research via The Guardian: http://www.guardian.co.uk/society/2011/feb/06/flu-universal-vaccine-test-success?CMP=twt_gu
According the to report on the medical site, WebMD, "such a vaccine could also help prevent pandemics such as the recent outbreaks of H1N1 swine flu.
Traditional flu vaccines target proteins that sit on the virus’s outside coat and harness the body’s existing antibodies to fight infection. However, these proteins tend to mutate, meaning that manufacturers have to develop new vaccines.
The new treatment targets proteins inside the flu virus that are common across all strains and use existing antiviral T cells to attack the virus."
http://www.webmd.boots.com/cold-and-flu/news/20110207/early-success-for-universal-flu-vaccine
Longer article about this research via The Guardian: http://www.guardian.co.uk/society/2011/feb/06/flu-universal-vaccine-test-success?CMP=twt_gu
Wednesday, February 2, 2011
Hand sanitizer for your nose!
According to a report by KABC, in Los Angeles, Nozin Nasal Sanitizer (http://www.nozin.com/) protects the lining of your nose from cold and flu viruses.
Dr. Lorraine Smith, and ear, nose and throat doc at Osborne Head and Neck Institute says, ""That product is actually supposed to kill 99.9 percent of the viruses and bacteria that you get exposed to, and it lasts about eight hours,"
http://abclocal.go.com/kabc/story?section=news/health/your_health&id=7933690
Dr. Lorraine Smith, and ear, nose and throat doc at Osborne Head and Neck Institute says, ""That product is actually supposed to kill 99.9 percent of the viruses and bacteria that you get exposed to, and it lasts about eight hours,"
http://abclocal.go.com/kabc/story?section=news/health/your_health&id=7933690
Tuesday, January 25, 2011
If you survived Swine Flu, you may now have super immunity, reports National Institute of Health
A study published in the Journal of Experimental Medicine (http://jem.rupress.org/content/208/1/181) indicates that people previously exposed to Swine Flu (H1N1) may have a super immunity to multiple strains of the flu, reports the National Institute of Health (http://www.niaid.nih.gov/news/newsreleases/2011/Pages/H1N1Bcell.aspx).
Thus, the potential for developing a "pan influenza vaccine" is theoretically possible.
According to the report on the National Institute of Allergy & Infectious Diseases website: "The investigators speculate that multiple exposures to seasonal influenza viruses and influenza vaccines over the years have given rise to memory cells that recognize the conserved regions of the virus. After a person is infected with 2009 H1N1, these cells become the source of antibody-producing plasmablasts. While broadly neutralizing antibodies have rarely been seen in people after exposure to seasonal viruses or vaccines, this study suggests that the outcome of 2009 H1N1 infection is different. Overall, the study shows that 2009 H1N1 can induce broadly protective human antibodies that bind to parts of the influenza virus that vary little from strain to strain, providing a potential immune target for use in a universal influenza vaccine."
And, mice used in experiments were found to be protected from lethal doses of Swine Flu and two other strains of flu. Thank goodness the mice are safe!
Thus, the potential for developing a "pan influenza vaccine" is theoretically possible.
According to the report on the National Institute of Allergy & Infectious Diseases website: "The investigators speculate that multiple exposures to seasonal influenza viruses and influenza vaccines over the years have given rise to memory cells that recognize the conserved regions of the virus. After a person is infected with 2009 H1N1, these cells become the source of antibody-producing plasmablasts. While broadly neutralizing antibodies have rarely been seen in people after exposure to seasonal viruses or vaccines, this study suggests that the outcome of 2009 H1N1 infection is different. Overall, the study shows that 2009 H1N1 can induce broadly protective human antibodies that bind to parts of the influenza virus that vary little from strain to strain, providing a potential immune target for use in a universal influenza vaccine."
And, mice used in experiments were found to be protected from lethal doses of Swine Flu and two other strains of flu. Thank goodness the mice are safe!
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